Neuroimaging in dementia: a brief review. doi:10.3233/JAD-170991īanerjee D, Muralidharan A, Hakim Mohammed AR, Malik BH. The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): modifications and responsiveness in pre-dementia populations. Kueper JK, Speechley M, Montero-odasso M. The MoCA has a maximum score of 30, and anything below 24 is a sign of cognitive impairment. It does so based on 11 questions that evaluate seven domains of cognitive function.
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The usfulness of the SLUMS test for diagnosis of mild cognitive impairment and dementia. The MoCA test is a simple, in-office test that can detect mild cognitive impairment and the early onset of dementia. The Saint Louis University mental status examination is better than the mini-mental state examination to determine the cognitive impairment in Turkish elderly people. Kaya D, Isik AT, Usarel C, Soysal P, Ellidokuz H, Grossberg GT. Detecting change over time: a comparison of the SLUMS examination and the MMSE in older adults at risk for cognitive decline. Combining the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) with the MMSE did not improve diagnostic utility.Howland M, Tatsuoka C, Smyth KA, Sajatovic M.
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Use of a cut-off lower than that specified in the index study may be required to improve overall test accuracy and specificity for some loss of sensitivity in populations with a high prior probability of cognitive impairment. We searched MEDLINE, PSYCInfo, EMBASE, and Cochrane CENTRAL (19952021) for studies comparing the MoCA with validated diagnostic criteria to identify MCI in general practice. In a memory clinic population, MoCA proved sensitive for the diagnosis of cognitive impairment. This systematic review evaluates the accuracy of the Montreal Cognitive Assessment (MoCA) for detecting mild cognitive impairment (MCI). Combining MoCA with the MMSE - either in series or in parallel - did not improve diagnostic utility above that with either test alone. The Montreal Cognitive Assessment (MoCA) is a quick, paper-based tool often used in clinical settings that might be useful in identifying certain populations who may benefit most from further FTD testing, whether they are cognitively impaired or not. Downward adjustment of the MoCA cut-off to ≥20/30 maximized test accuracy and improved specificity (0.95) for some loss of sensitivity (0.63). In Table 3, we present data of calculated cut-off scores 1, 1.5 and 2 SD below the mean score.
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The mean MoCA score for women was 26.1 (SD 2.3) and for men 25.7 (SD 2.4) ( p 0.006). Using the cut-offs for MoCA and MMSE specified in the index paper (≥26/30), MoCA was more sensitive than MMSE (0.97 vs 0.65) but less specific (0.60 vs 0.89), with better diagnostic accuracy (area under Receiver Operating Characteristic curve 0.91 vs 0.83). Normative scores for the different parts of MoCA stratified according to age and education are provided in Supplementary Table 1. MoCA proved acceptable to patients and was quick and easy to use. Patients were diagnosed using standard clinical diagnostic criteria for dementia (DSM-IV) and mild cognitive impairment (MCI cognitive impairment prevalence = 43%) independent of MoCA test scores.
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This was a pragmatic prospective study of consecutive referrals attending a memory clinic (n = 150) over an 18-month period. This aim of this study was to assess the clinical utility of the Montreal Cognitive Assessment (MoCA) as a screening instrument for cognitive impairment in patients referred to a memory clinic, alone and in combination with the Mini-Mental State Examination (MMSE).